USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: P09417 USC-OGP 2-DE database:  P09417 P09417 General information about the entry View entry in simple text format Entry name DHPR_HUMAN Primary accession number P09417 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Dihydropteridine reductase; EC=1.5.1.34; AltName: Full=HDHPR; AltName: Full=Quinoid dihydropteridine reductase; AltName: Full=Short chain dehydrogenase/reductase family 33C member 1;. Gene name Name=QDPR Synonyms=DHPR, SDR33C1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1282: pI=6.89; Mw=26515 Cross-references UniProtKB/Swiss-Prot P09417; DHPR_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name DHPR_HUMAN Primary accession number P09417 Secondary accession number(s) A8K158 B3KW71 Q53F52 Q9H3M5 Sequence was last modified on  November 28, 2006 (version 2) Annotations were last modified on  March 15, 2017 (version 192) Name and origin of the protein Description RecName: Full=Dihydropteridine reductase; EC=1.5.1.34; AltName: Full=HDHPR; AltName: Full=Quinoid dihydropteridine reductase; AltName: Full=Short chain dehydrogenase/reductase family 33C member 1; Gene name Name=QDPR Synonyms=DHPR, SDR33C1 Encoded on Name=QDPR; Synonyms=DHPR, SDR33C1 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Direct protein sequencing; Disease mutation; NADP; Oxidoreductase; Phenylketonuria; Polymorphism; Reference proteome; Tetrahydrobiopterin biosynthesis. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X04882; CAA28571.1; -; mRNA EMBL M16447; AAA52305.1; -; mRNA EMBL AJ006239; CAA06930.1; -; Genomic_DNA EMBL AJ006240; CAA06930.1; JOINED; Genomic_DNA EMBL AJ006241; CAA06930.1; JOINED; Genomic_DNA EMBL AJ006242; CAA06930.1; JOINED; Genomic_DNA EMBL AJ006243; CAA06930.1; JOINED; Genomic_DNA EMBL AJ006244; CAA06930.1; JOINED; Genomic_DNA EMBL AJ006245; CAA06930.1; JOINED; Genomic_DNA EMBL AB053170; BAB20429.1; -; Genomic_DNA EMBL AK124382; BAG54033.1; -; mRNA EMBL AK289773; BAF82462.1; -; mRNA EMBL AK223437; BAD97157.1; -; mRNA EMBL AC093600; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471069; EAW92777.1; -; Genomic_DNA EMBL CH471069; EAW92778.1; -; Genomic_DNA EMBL BC000576; AAH00576.1; -; mRNA CCDS CCDS3421.1; -. [P09417-1]; . CCDS CCDS77904.1; -. [P09417-2]; . PIR A93655; RDHUP; . RefSeq NP_000311.2; NM_000320.2. [P09417-1]; . RefSeq NP_001293069.1; NM_001306140.1. [P09417-2]; . UniGene Hs.75438; -; . PDB 1HDR; X-ray; 2.50 A; A=1-244 PDBsum 1HDR; -; . ProteinModelPortal P09417; -; . SMR P09417; -; . BioGrid 111798; 26; . IntAct P09417; 4; . MINT MINT-5002411; -; . STRING 9606.ENSP00000281243; -; . BindingDB P09417; -; . ChEMBL CHEMBL3730; -; . DrugBank DB03814; 2-(N-Morpholino)-Ethanesulfonic Acid; . DrugBank DB00157; NADH; . iPTMnet P09417; -; . PhosphoSitePlus P09417; -; . BioMuta QDPR; -; . DMDM 118572639; -; . REPRODUCTION-2DPAGE IPI00014439; -; . UCD-2DPAGE P09417; -; . EPD P09417; -; . MaxQB P09417; -; . PaxDb P09417; -; . PeptideAtlas P09417; -; . PRIDE P09417; -; . DNASU 5860; -; . Ensembl ENST00000281243; ENSP00000281243; ENSG00000151552. [P09417-1]; . Ensembl ENST00000428702; ENSP00000390944; ENSG00000151552. [P09417-2]; . GeneID 5860; -; . KEGG hsa:5860; -; . UCSC uc003gpd.4; human. [P09417-1]; . CTD 5860; -; . DisGeNET 5860; -; . GeneCards QDPR; -; . HGNC HGNC:9752; QDPR; . HPA HPA058951; -; . HPA HPA065649; -; . MalaCards QDPR; -; . MIM 261630; phenotype; . MIM 612676; gene; . neXtProt NX_P09417; -; . OpenTargets ENSG00000151552; -; . Orphanet 226; Dihydropteridine reductase deficiency; . PharmGKB PA34094; -; . eggNOG KOG4022; Eukaryota; . eggNOG ENOG4111D6J; LUCA; . GeneTree ENSGT00390000000470; -; . HOGENOM HOG000232194; -; . HOVERGEN HBG001000; -; . InParanoid P09417; -; . KO K00357; -; . OMA NRKSMPD; -; . OrthoDB EOG091G0ILG; -; . PhylomeDB P09417; -; . TreeFam TF105932; -; . BioCyc MetaCyc:HS07746-MONOMER; -; . BRENDA 1.5.1.34; 2681; . Reactome R-HSA-71182; Phenylalanine and tyrosine catabolism; . SABIO-RK P09417; -; . ChiTaRS QDPR; human; . EvolutionaryTrace P09417; -; . GeneWiki QDPR; -; . GenomeRNAi 5860; -; . PRO PR:P09417; -; . Proteomes UP000005640; Chromosome 4; . Bgee ENSG00000151552; -; . CleanEx HS_QDPR; -; . ExpressionAtlas P09417; baseline and differential; . Genevisible P09417; HS; . GO GO:0005737; C:cytoplasm; IDA:LIFEdb; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IEA:Ensembl; . GO GO:0043005; C:neuron projection; IEA:Ensembl; . GO GO:0004155; F:6; 7-dihydropteridine reductase activity; EXP:Reactome GO GO:0009055; F:electron carrier activity; TAS:UniProtKB; . GO GO:0070404; F:NADH binding; IEA:Ensembl; . GO GO:0070402; F:NADPH binding; IEA:Ensembl; . GO GO:0006520; P:cellular amino acid metabolic process; TAS:ProtInc; . GO GO:0035690; P:cellular response to drug; IEA:Ensembl; . GO GO:0051066; P:dihydrobiopterin metabolic process; TAS:ProtInc; . GO GO:0006559; P:L-phenylalanine catabolic process; TAS:Reactome; . GO GO:0001889; P:liver development; IEA:Ensembl; . GO GO:0010044; P:response to aluminum ion; IEA:Ensembl; . GO GO:0033762; P:response to glucagon; IEA:Ensembl; . GO GO:0010288; P:response to lead ion; IEA:Ensembl; . GO GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:UniProtKB-KW; . Gene3D 3.40.50.720; -; 1; . InterPro IPR016040; NAD(P)-bd_dom; . InterPro IPR020904; Sc_DH/Rdtase_CS; . InterPro IPR002347; SDR_fam; . Pfam PF00106; adh_short; 1; . SUPFAM SSF51735; SSF51735; 1; . PROSITE PS00061; ADH_SHORT; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]